John Lysack

John Lysack

About John Lysack



Neuroradiology, Head and Neck Imaging


Queen’s University


Massachusetts General Hospital, Harvard University


Clinical Associate Professor




FRCPC (Diagnostic Radiology),

FRCPC (Founder in Neuroradiology),

DABR (Diagnostic Radiology)



Head and Neck Tumour Board


Canadian Society of Neuroradiology

American Society of Head and Neck Radiologists


My research interests are in the areas of development of imaging techniques and processes to improve diagnostic accuracy and clinical outcomes in patients with head and neck cancer.   

Sabiq F, Huang K, Patel A, Banerjee R, Debenham B, Lau H, Skarsgard D, Chen G, Lysack JT, Quon HC. Novel imaging classification system of nodal disease in human papillomavirus-mediated oropharyngeal squamous cell carcinoma prognostic of patient outcomes. Head Neck. 2021 Jun;43(6):1854-1863. doi: 10.1002/hed.26657. Epub 2021 Feb 26. PMID: 33638232.

Hinther A, Samson N, Lau H, Quon H, Banerjee R, Lysack JT, Grendarova P, Matthews TW, Randall DR. Volumetric changes in pharyngeal structures following head and neck cancer chemoradiation therapy. Laryngoscope. 2020 Mar;130(3):597-602. doi: 10.1002/lary.28164. Epub 2019 Jul 1. PMID: 31260128.

Cox E, Ghasemloonia A, Nakoneshny SC, Zareinia K, Hudon M, Lysack JT, Sutherland GR, Dort JC. Improved transoral surgical tool design by CT measurements of the oral cavity and pharynx. J Robot Surg. 2017 Jun;11(2):179-185. doi: 10.1007/s11701-016-0639-z. Epub 2016 Sep 23. PMID: 27664143.    Dang M, Lysack JT, Wu T, Matthews TW, Chandarana SP, Brockton NT, Bose P, Bansal G, Cheng H, Mitchell JR, Dort JC. MRI texture analysis predicts p53 status in head and neck squamous cell carcinoma. AJNR Am J Neuroradiol. 2015 Jan;36(1):166-70. doi: 10.3174/ajnr.A4110. Epub 2014 Sep 25. PMID: 25258367; PMCID: PMC7965921.

Lysack JT, Hoy M, Hudon ME, Nakoneshny SC, Chandarana SP, Matthews TW, Dort JC. Impact of neuroradiologist second opinion on staging and management of head and neck cancer. J Otolaryngol Head Neck Surg. 2013 Jun 5;42(1):39. doi: 10.1186/1916-0216-42-39. PMID: 23739037; PMCID: PMC3680178.


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